Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 6/20 | 0.76 |
| ▸ | HTR1A | P08908 | 7/20 | 0.68 |
| ▸ | HTR7 | P34969 | 3/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26508398 | 0.87 | MPO (0.94) | MPOHTR1AHTR7SLC6A4 | |
| SCHEMBL733997 | 0.87 | MPO (1.00) | MPOHTR1AHTR7 | |
| SCHEMBL733711 | 0.85 | MPO (0.97) | MPOHTR1AHTR7 | |
| SCHEMBL27836200 | 0.84 | MPO (1.00) | MPOHTR1AHTR7SLC6A4 | |
| SCHEMBL27836191 | 0.83 | MPO (0.78) | MPOHTR1AHTR7SLC6A4 | |
| SCHEMBL9033157 | 0.81 | HTR2A (0.74) | HTR1AHTR7SLC6A4 | |
| SCHEMBL17525734 | 0.80 | MPO (0.64) | MPOHTR1ASLC6A4 | |
| SCHEMBL8557700 | 0.79 | MPO (0.71) | MPOHTR1AHTR7SLC6A4 | |
| SCHEMBL11536718 | 0.79 | RAB9A (0.70) | MPOHTR1A | |
| SCHEMBL9541312 | 0.78 | TSHR (0.60) | MPOHTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014084-A2 | PIPERIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |