Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 3/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542392 | 0.84 | PGR (0.41) | PGRARLMNAESR1SLC6A4 | |
| SCHEMBL9541221 | 0.84 | — | — | |
| SCHEMBL9541223 | 0.78 | PDK1 (0.43) | PDK1PDK2PDK3PDK4PGR | |
| SCHEMBL9542422 | 0.74 | CYP3A4 (0.39) | PGRARLMNAESR1 | |
| SCHEMBL9541199 | 0.71 | PGR (0.58) | PGRARLMNAESR1SLC6A4 | |
| SCHEMBL9128149 | 0.69 | CYP3A4 (0.36) | PGRARLMNAESR1 | |
| SCHEMBL9128153 | 0.69 | CYP3A4 (0.36) | PGRARLMNAESR1 | |
| SCHEMBL9541966 | 0.65 | PDK1 (0.43) | PDK1PDK2PDK3PDK4PGR | |
| SCHEMBL9124545 | 0.65 | SHBG (0.43) | PGRARLMNAESR1 | |
| SCHEMBL9124551 | 0.65 | SHBG (0.43) | PGRARLMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | claimed |
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |