Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544974 | 0.77 | KDM4E (0.40) | METAP2METAP1MMP2TSHRCHRM1 | |
| SCHEMBL358917 | 0.75 | L3MBTL1 (0.43) | MMP2TSHRKDM4EL3MBTL1HSP90AA1 | |
| SCHEMBL5182523 | 0.75 | LMNA (0.39) | METAP2METAP1MMP2TSHRCHRM1 | |
| SCHEMBL3970053 | 0.75 | HSP90AA1 (0.40) | METAP2METAP1MMP2TSHRKDM4E | |
| SCHEMBL8114833 | 0.75 | KDM4E (0.40) | METAP2METAP1MMP2TSHRCHRM1 | |
| SCHEMBL31167172 | 0.75 | LIMK1 (0.43) | MMP2TSHRKDM4EL3MBTL1HSP90AA1 | |
| SCHEMBL5183987 | 0.75 | LIMK1 (0.43) | MMP2TSHRKDM4EL3MBTL1HSP90AA1 | |
| SCHEMBL13857883 | 0.75 | PSMD14 (0.45) | METAP2METAP1MMP2TSHRCHRM1 | |
| SCHEMBL7114666 | 0.73 | KDM4E (0.48) | TSHRKDM4EL3MBTL1LMNAMAPT | |
| SCHEMBL29560247 | 0.73 | KDM4E (0.48) | TSHRKDM4EL3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645968-B | Fused ring compound containing two boron atoms and two oxygen family atoms and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2022-06-07 | — | — | CN | disclosed |
| CN-112645968-A | Fused ring compound containing two boron atoms and two oxygen family atoms and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2021-04-13 | — | — | CN | disclosed |
| CN-1076697-A | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LTD (GB) | 1993-09-29 | — | — | CN | disclosed |
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |