Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585668 | 0.88 | ALOX5 (0.49) | ALOX5ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9538830 | 0.88 | ALOX5 (0.65) | ALOX5ALDH1A1HTTHPGDMAPT | |
| SCHEMBL9539738 | 0.77 | ALOX5 (0.61) | ALOX5ALDH1A1HPGDMAPTPKM | |
| SCHEMBL9585017 | 0.77 | IKBKB (0.46) | ALOX5ALDH1A1KDM4EMAPTGFER | |
| SCHEMBL9538854 | 0.73 | IKBKB (0.42) | ALOX5MMP2MEN1KMT2A | |
| SCHEMBL15827525 | 0.71 | ALDH1A1 (0.54) | ALOX5ALDH1A1HTTHPGDKDM4E | |
| SCHEMBL9833394 | 0.70 | ALOX5 (0.74) | ALOX5ALDH1A1HTTHPGDKDM4E | |
| SCHEMBL9542504 | 0.70 | ALOX5 (0.60) | ALOX5ALDH1A1KDM4EMAPTMMP2 | |
| SCHEMBL9832912 | 0.69 | ALOX5 (0.43) | ALOX5MAPTMMP2SMN1; SMN2MEN1 | |
| SCHEMBL27990409 | 0.69 | ALDH1A1 (0.75) | ALOX5ALDH1A1HTTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | claimed |
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |