Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538854 | 0.95 | IKBKB (0.42) | IKBKBMMP2CNR1POLBRAB9A | |
| SCHEMBL9539740 | 0.88 | MMP2 (0.39) | MMP2ESRRGESR1ALOX5 | |
| SCHEMBL9584912 | 0.87 | CYP2E1 (0.45) | MMP2POLBRAB9AMEN1KMT2A | |
| SCHEMBL9539694 | 0.81 | RAB9A (0.39) | MMP2KDM4ERAB9AALOX5 | |
| SCHEMBL9539825 | 0.78 | ALOX5 (0.39) | MMP2ALOX5 | |
| SCHEMBL9541471 | 0.77 | ALOX5 (0.49) | MMP2MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL9584641 | 0.73 | MMP2 (0.37) | MMP2ALOX5 | |
| SCHEMBL9584629 | 0.72 | MMP2 (0.34) | MMP2ALOX5 | |
| SCHEMBL3306078 | 0.72 | IKBKB (0.58) | IKBKBCNR1MAPTALDH1A1POLB | |
| SCHEMBL9583758 | 0.72 | MMP2 (0.33) | MMP2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |