Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544012 | 0.91 | PRKD3 (0.43) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL9534442 | 0.76 | DRD3 (0.61) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9535816 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL9537199 | 0.75 | LMNA (0.61) | GSK3BALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9543963 | 0.70 | KDM4E (0.32) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL9757220 | 0.70 | PRKD3 (0.41) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL30866391 | 0.68 | KDM4E (0.63) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL6703755 | 0.67 | KDM4E (0.62) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL30686874 | 0.67 | ALDH1A1 (0.59) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL9541515 | 0.67 | MEN1 (0.46) | GSK3BALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013090-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES AND PROCESSES FOR PREPARING SAME | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |