Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 8/20 | 0.68 |
| ▸ | PARP1 | P09874 | 8/20 | 0.58 |
| ▸ | IP6K3 | Q96PC2 | 3/20 | 0.57 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.54 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739920 | 0.91 | IP6K1 (0.61) | IP6K1PARP1IP6K3IP6K2PDPK1 | |
| SCHEMBL4252782 | 0.87 | PARP1 (0.69) | IP6K1PARP1IP6K3IP6K2PDPK1 | |
| SCHEMBL4252776 | 0.82 | PARP1 (0.72) | IP6K1PARP1IP6K3IP6K2CHEK1 | |
| SCHEMBL24155902 | 0.80 | ACVR1 (0.61) | IP6K1PARP1IP6K3IP6K2PDPK1 | |
| SCHEMBL19373198 | 0.80 | IP6K1 (0.61) | IP6K1PARP1IP6K3IP6K2PDPK1 | |
| SCHEMBL1257333 | 0.80 | PARP1 (0.63) | IP6K1PARP1IP6K3IP6K2PDPK1 | |
| SCHEMBL1799380 | 0.78 | MMP12 (0.62) | SMN1; SMN2CHEK1 | |
| SCHEMBL29770425 | 0.78 | MMP12 (0.62) | SMN1; SMN2CHEK1 | |
| SCHEMBL7980737 | 0.78 | ACVR1 (0.67) | IP6K1PARP1IP6K3IP6K2PDPK1 | |
| SCHEMBL17950454 | 0.76 | MAOA (0.43) | IP6K1SMN1; SMN2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4920224-A | CHEMICAL INTERMEDIATES | PFIZER INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4849518-A | ANTIPROTOZOA IN POULTRY | PFIZER INC. (US) | 1989-07-18 | — | — | US | disclosed |
| US-4762838-A | Quinazolin-4(3H)-one derivatives as anticoccidial agents | PFIZER INC. (US) | 1988-08-09 | — | — | US | disclosed |