Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL40031 | 0.87 | TSHR (0.47) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| Propylene Glycol SCHEMBL6398929 | 0.87 | TSHR (0.47) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| Propylene Glycol SCHEMBL2120984 | 0.87 | TSHR (0.47) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL49462 | 0.87 | ALDH1A1 (0.47) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1946788 | 0.84 | TSHR (0.52) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| Isopropyl Alcohol SCHEMBL27564110 | 0.84 | TSHR (0.52) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| Isobutane SCHEMBL1759584 | 0.84 | TSHR (0.56) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL7519033 | 0.83 | TSHR (0.44) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| Propylene Glycol SCHEMBL9690765 | 0.83 | TSHR (0.48) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL15797057 | 0.82 | TSHR (0.50) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015122-A1 | MEDICAL GRADE ADHESIVES AND THEIR PREPARATION | THE UNIVERSITY OF AKRON (US) | 1993-08-05 | — | — | WO | disclosed |
| US-5175246-A | Reacting aliphatic diamines with diepoxide | UNIVERSITY OF AKRON, THE (US) | 1992-12-29 | — | — | US | disclosed |