Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2941157 | 0.89 | PLG (0.45) | HTR7PLGPLAUARSLC6A2 | |
| SCHEMBL3355607 | 0.84 | HTR7 (0.49) | HTR7PLGPLAUARSLC6A2 | |
| SCHEMBL2479169 | 0.82 | HTR7 (0.47) | HTR7PLGPLAUSLC6A2CYP19A1 | |
| SCHEMBL30785020 | 0.81 | MAPT (0.51) | HTR7PLGPLAUARSLC6A2 | |
| SCHEMBL29167245 | 0.81 | MAPT (0.51) | HTR7PLGPLAUARSLC6A2 | |
| SCHEMBL27768896 | 0.81 | KRAS (0.47) | HTR7PLGPLAUARSLC6A2 | |
| SCHEMBL16371052 | 0.81 | PLG (0.46) | HTR7PLGPLAUSLC6A2CYP19A1 | |
| SCHEMBL30672928 | 0.81 | PLG (0.46) | HTR7PLGPLAUSLC6A2CYP19A1 | |
| SCHEMBL2420811 | 0.81 | CYP1A2 (0.53) | HTR7PLGPLAUARSLC6A2 | |
| SCHEMBL31735481 | 0.81 | AR (0.50) | HTR7PLGPLAUARSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010119-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |
| EP-0542497-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |