SCHEMBL31735481

SCHEMBL31735481

CC(C)(N)Cn1ccc2cc([N+](=O)[O-])ccc21

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.50
PLG P00747 1/20 0.46
PLAU P00749 1/20 0.46
KRAS P01116 1/20 0.45
SLC6A2 P23975 1/20 0.43
HTR7 P34969 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP19A1 P11511 1/20 0.40
GLS O94925 1/20 0.39
MAPT P10636 3/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2941157 0.86 PLG (0.45) ARPLGPLAUKRASSLC6A2
SCHEMBL26621625 0.86 AR (0.52) ARPLGPLAUKRASSLC6A2
SCHEMBL20986010 0.86 AR (0.52) ARPLGPLAUKRASSLC6A2
SCHEMBL26621473 0.86 AR (0.52) ARPLGPLAUKRASSLC6A2
SCHEMBL30764979 0.86 AR (0.52) ARPLGPLAUKRASSLC6A2
SCHEMBL18491500 0.83 AR (0.49) ARPLGPLAUKRASSLC6A2
SCHEMBL2420811 0.81 CYP1A2 (0.53) ARPLGPLAUKRASSLC6A2
SCHEMBL9541765 0.81 HTR7 (0.46) ARPLGPLAUKRASSLC6A2
SCHEMBL3355607 0.78 HTR7 (0.49) ARPLGPLAUKRASSLC6A2
SCHEMBL12475322 0.78 PLG (0.51) ARPLGPLAUKRASSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 WO disclosed