Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | SNCA | P37840 | 7/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 5/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540868 | 0.86 | MAPT (0.47) | APPMAPTSNCACCKBRPTPN1 | |
| SCHEMBL9540886 | 0.86 | MAPT (0.47) | APPMAPTSNCACCKBRPTPN1 | |
| SCHEMBL9774421 | 0.78 | CCKBR (0.43) | APPMAPTSNCACCKBRPTPN1 | |
| SCHEMBL9543560 | 0.78 | CCKBR (0.43) | APPMAPTSNCACCKBRPTPN1 | |
| SCHEMBL9774427 | 0.77 | TRPA1 (0.42) | APPMAPTSNCAPTPN1KMT2A | |
| SCHEMBL9541539 | 0.77 | TRPA1 (0.42) | APPMAPTSNCAPTPN1KMT2A | |
| SCHEMBL9541006 | 0.77 | CCKBR (0.43) | APPMAPTSNCACCKBRPTPN1 | |
| SCHEMBL9774452 | 0.75 | EP300 (0.45) | APPMAPTSNCAPTPN1KMT2A | |
| SCHEMBL9540933 | 0.75 | EP300 (0.45) | APPMAPTSNCAPTPN1KMT2A | |
| SCHEMBL9540923 | 0.74 | EP300 (0.48) | PTPN1KMT2AMEN1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012786-A1 | INDOLINONE DERIVATIVES | HOWARD HARRY R JR (US) | 1993-07-08 | — | — | WO | disclosed |