Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859937 | 0.87 | ALOX5 (0.58) | ALOX5F2RL1CALM1LTB4RPOLB | |
| SCHEMBL933946 | 0.85 | ALOX5 (0.59) | ALOX5F2RL1CALM1LTB4RPOLB | |
| SCHEMBL13522667 | 0.85 | ALOX5 (0.59) | ALOX5F2RL1CALM1LTB4RPOLB | |
| SCHEMBL1237172 | 0.85 | F2RL1 (0.62) | ALOX5F2RL1CALM1LTB4RPOLB | |
| SCHEMBL20019549 | 0.83 | ALOX5 (0.61) | ALOX5F2RL1CALM1POLBIGF1R | |
| SCHEMBL3675681 | 0.83 | ALOX5 (0.57) | ALOX5F2RL1CALM1KMT2AL3MBTL1 | |
| SCHEMBL9484086 | 0.82 | LTB4R (0.69) | ALOX5F2RL1CALM1LTB4R | |
| SCHEMBL9235000 | 0.82 | ALOX5 (0.59) | ALOX5F2RL1CALM1LTB4RPOLB | |
| SCHEMBL11637942 | 0.82 | ALOX5 (0.59) | ALOX5F2RL1CALM1LTB4RPOLB | |
| SCHEMBL8001859 | 0.82 | LTB4R (0.69) | ALOX5F2RL1CALM1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993000359-A1 | MODIFIED PEPTIDES TRANSPORTABLE INTO THE CENTRAL NERVOUS SYSTEM | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-01-07 | — | — | WO | disclosed |