Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274985 | 0.95 | ALOX5 (0.66) | F2RL1ALOX5POLBCALM1ALDH1A1 | |
| SCHEMBL9859937 | 0.88 | ALOX5 (0.58) | F2RL1ALOX5POLBCALM1ALDH1A1 | |
| SCHEMBL1445627 | 0.87 | F2RL1 (0.73) | F2RL1ALOX5POLBALDH1A1 | |
| SCHEMBL15522689 | 0.86 | CYP4F2 (0.64) | F2RL1ALOX5CALM1ALDH1A1 | |
| SCHEMBL20683866 | 0.86 | ALOX5 (0.56) | F2RL1ALOX5POLBCALM1ALDH1A1 | |
| SCHEMBL17593315 | 0.85 | CYP4F2 (0.46) | F2RL1ALOX5ALDH1A1 | |
| SCHEMBL7999711 | 0.85 | ALOX5 (0.59) | F2RL1ALOX5CALM1 | |
| SCHEMBL9542322 | 0.85 | ALOX5 (0.55) | F2RL1ALOX5POLBCALM1LTB4R | |
| SCHEMBL22921868 | 0.85 | TSHR (0.58) | F2RL1ALOX5ALDH1A1 | |
| SCHEMBL20683764 | 0.85 | F2RL1 (0.53) | F2RL1ALOX5POLBCALM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230403929-A1 | PHOTOELECTRIC CONVERSION DEVICE AND IMAGING APPARATUS | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2023-12-14 | — | — | US | disclosed |
| US-20230403929-A1 | PHOTOELECTRIC CONVERSION DEVICE AND IMAGING APPARATUS | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2023-12-14 | — | — | US | disclosed |
| US-20230127655-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-04-27 | — | — | US | disclosed |
| US-20170073370-A1 | BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. | 2017-03-16 | — | — | US | disclosed |
| US-20140249073-A1 | BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC (US) | 2014-09-04 | — | — | US | disclosed |
| US-7879843-B2 | matrix metallo-proteinase inhibitors such as (-)-ethyl 4-[2-(hydroxyamino)-2-oxoethyl]-2-[3-(4-methoxyphenyl)propyl]-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate, used for the treatment of osteoarthritis or rheumatoid arthritis | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-02-01 | — | — | US | disclosed |
| US-7879843-B2 | matrix metallo-proteinase inhibitors such as (-)-ethyl 4-[2-(hydroxyamino)-2-oxoethyl]-2-[3-(4-methoxyphenyl)propyl]-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate, used for the treatment of osteoarthritis or rheumatoid arthritis | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-02-01 | — | — | US | disclosed |
| US-7879843-B2 | matrix metallo-proteinase inhibitors such as (-)-ethyl 4-[2-(hydroxyamino)-2-oxoethyl]-2-[3-(4-methoxyphenyl)propyl]-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate, used for the treatment of osteoarthritis or rheumatoid arthritis | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-02-01 | — | — | US | disclosed |
| EP-1726587-B1 | BENZOTHIAZIN-3-ONE COMPOUND AND INTERMEDIATE THEREFOR | DAINIPPON SUMITOMO PHARMA CO (JP) | 2010-09-01 | — | — | EP | disclosed |
| EP-1726587-B1 | BENZOTHIAZIN-3-ONE COMPOUND AND INTERMEDIATE THEREFOR | DAINIPPON SUMITOMO PHARMA CO (JP) | 2010-09-01 | — | — | EP | disclosed |
| US-20100009976-A1 | BENZOTHIAZIN-3-ONE COMPOUND AND INTERMEDIATE THEREFOR | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| US-20100009976-A1 | BENZOTHIAZIN-3-ONE COMPOUND AND INTERMEDIATE THEREFOR | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| US-20100009976-A1 | BENZOTHIAZIN-3-ONE COMPOUND AND INTERMEDIATE THEREFOR | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| US-7598240-B2 | Benzothiazin-3-one compound and intermediate therefor | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-10-06 | — | — | US | disclosed |
| US-7598240-B2 | Benzothiazin-3-one compound and intermediate therefor | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-10-06 | — | — | US | disclosed |
| US-7598240-B2 | Benzothiazin-3-one compound and intermediate therefor | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-10-06 | — | — | US | disclosed |
| US-20080058321-A1 | BENZOTHIAZIN-3-ONE COMPOUND AND INTERMEDIATE THEREFOR | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-03-06 | — | — | US | disclosed |
| US-20080058321-A1 | BENZOTHIAZIN-3-ONE COMPOUND AND INTERMEDIATE THEREFOR | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-03-06 | — | — | US | disclosed |
| US-20080058321-A1 | BENZOTHIAZIN-3-ONE COMPOUND AND INTERMEDIATE THEREFOR | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-03-06 | — | — | US | disclosed |
| EP-1726587-A1 | BENZOTHIAZIN-3-ONE COMPOUND AND INTERMEDIATE THEREFOR | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230403929-A1 | PHOTOELECTRIC CONVERSION DEVICE AND IMAGING APPARATUS | TYR, FTO, ZKSCAN2 | F2RL1 1702/4885ALOX5 3012/4885POLB 1848/4885 |
| US-20140249073-A1 | BROAD SPECTRUM ANTIBIOTICS | SPAST, NPEPPS, SPOUT1 | F2RL1 3169/4885ALOX5 4787/4885POLB 3259/4885 |
| US-20100009976-A1 | BENZOTHIAZIN-3-ONE COMPOUND AND INTERMEDIATE THEREFOR | HDAC11, HDAC8, MMP11 | F2RL1 2385/4885ALOX5 1077/4885POLB 1725/4885 |
| US-20170073370-A1 | BROAD SPECTRUM ANTIBIOTICS | SPAST, NPEPPS, SPOUT1 | F2RL1 3169/4885ALOX5 4787/4885POLB 3259/4885 |
| US-20230127655-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | F2RL1 1846/4885ALOX5 3605/4885POLB 2183/4885 |
| US-20080058321-A1 | BENZOTHIAZIN-3-ONE COMPOUND AND INTERMEDIATE THEREFOR | HDAC11, HDAC8, MMP11 | F2RL1 2385/4885ALOX5 1077/4885POLB 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.