Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917213 | 0.87 | MAOA (0.37) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL9449382 | 0.83 | TRPM5 (0.37) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL9449414 | 0.76 | HRH3 (0.46) | TDO2KMT2AMEN1CA1CA2 | |
| Hydrochloric Acid SCHEMBL7609388 | 0.76 | HTR2A (0.42) | TDO2KMT2AMEN1CA1CA2 | |
| SCHEMBL17067722 | 0.76 | CNR1 (0.38) | NPC1TP53 | |
| SCHEMBL14327287 | 0.74 | ALDH1A1 (0.36) | TRPM5MAOBALDH1A1HPGDHSD17B10 | |
| SCHEMBL14396288 | 0.74 | MAP2K4 (0.35) | CA1CA2CA4CA7CA9 | |
| SCHEMBL2938396 | 0.73 | LDHA (0.32) | KMT2ACYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9449431 | 0.72 | EGFR (0.45) | KMT2AMEN1CYP1A2ALDH1A1HPGD | |
| SCHEMBL10147112 | 0.72 | PPIA (0.33) | KMT2AMEN1MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011764-A1 | FLUORENYL DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCIOS NOVA INC. (US) | 1993-06-24 | — | — | WO | disclosed |