SCHEMBL9542532

SCHEMBL9542532

COC(=S)c1sc2nc(C)ncc2c1O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
HTT P42858 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9542508 0.80 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2KDM4EMAPTHPGD
SCHEMBL5218755 0.64 LMNA (0.33) SMN1; SMN2MAPTHTTHPGD
SCHEMBL13239827 0.62 KDM4E (0.44) ALDH1A1SMN1; SMN2KDM4EMAPTHTT
SCHEMBL5211853 0.62 KDM4E (0.33) ALDH1A1KDM4E
SCHEMBL21240395 0.62 LMNA (0.32)
SCHEMBL21704211 0.60 KDM4E (0.33) ALDH1A1SMN1; SMN2KDM4EMAPTHPGD
SCHEMBL21703985 0.60 LIMK1 (0.34) ALDH1A1SMN1; SMN2KDM4EMAPTHPGD
SCHEMBL4126822 0.60 IKBKB (0.52) ALDH1A1SMN1; SMN2KDM4EMAPTHTT
SCHEMBL1019279 0.59 LMNA (0.30)
SCHEMBL16919863 0.58 GPR3 (0.45) ALDH1A1SMN1; SMN2KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993013664-A2 BIHETEROCYCLIC FUNGICIDAL COMPOUNDS SCHERING AGROCHEMICALS LIMITED (GB) 1993-07-22 WO disclosed