Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 1/20 | 0.62 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.59 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074365 | 1.00 | RRM1 (0.62) | RRM1DPP7CES2GNAI3GNAO1 | |
| SCHEMBL28617248 | 1.00 | RRM1 (0.62) | RRM1DPP7CES2GNAI3GNAO1 | |
| SCHEMBL6320398 | 1.00 | RRM1 (0.62) | RRM1DPP7CES2GNAI3GNAO1 | |
| SCHEMBL25469804 | 0.91 | GNAI3 (0.57) | RRM1DPP7CES2GNAI3GNAO1 | |
| SCHEMBL165368 | 0.90 | FAAH (0.57) | RRM1CHRM1 | |
| SCHEMBL27468902 | 0.90 | FAAH (0.57) | RRM1CHRM1 | |
| SCHEMBL6271110 | 0.89 | GNAI3 (0.64) | RRM1DPP7CES2GNAI3GNAO1 | |
| SCHEMBL32676289 | 0.89 | GNAI3 (0.64) | RRM1DPP7CES2GNAI3GNAO1 | |
| SCHEMBL904746 | 0.88 | CES2 (0.55) | DPP7CES2GNAI3GNAO1GNAI1 | |
| SCHEMBL5319167 | 0.88 | CES2 (0.55) | RRM1DPP7CES2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011758-A1 | N-AMINOALKYL AMIDE INHIBITORS OF PROTEIN KINASE C | SPHINX PHARMACEUTICALS CORPORATION (US) | 1993-06-24 | — | — | WO | disclosed |