Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382993 | 1.00 | ADRA1A (0.46) | ADRA1AADRA1DADRA1BKMT2AP2RX7 | |
| SCHEMBL2575919 | 0.86 | P2RX7 (0.49) | ADRA1AKMT2AP2RX7 | |
| SCHEMBL2575921 | 0.86 | P2RX7 (0.49) | ADRA1AKMT2AP2RX7 | |
| SCHEMBL11949260 | 0.86 | P2RX7 (0.49) | ADRA1AKMT2AP2RX7 | |
| SCHEMBL8535575 | 0.80 | KMT2A (0.55) | ADRA1AKMT2AP2RX7USP2ALDH1A1 | |
| SCHEMBL5166634 | 0.80 | KMT2A (0.55) | ADRA1AKMT2AP2RX7USP2ALDH1A1 | |
| SCHEMBL20334501 | 0.80 | ADRA1A (0.48) | ADRA1AADRA1DADRA1BKMT2AUSP2 | |
| SCHEMBL28637480 | 0.79 | ADRA1A (0.40) | ADRA1AADRA1DADRA1BKMT2AP2RX7 | |
| SCHEMBL13331904 | 0.79 | ALDH1A1 (0.48) | ADRA1AADRA1DADRA1BKMT2AUSP2 | |
| SCHEMBL6694973 | 0.79 | ACE (0.44) | KMT2AP2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009120-A1 | PROCESS FOR THE PREPARATION OF CONDENSED IMIDAZOLES | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1993-05-13 | — | — | WO | disclosed |