Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 6/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430926 | 0.75 | ALDH1A1 (0.49) | ESRRBESRRGUSP14MEN1KMT2A | |
| SCHEMBL1527572 | 0.69 | IDO1 (0.42) | USP14NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL9110624 | 0.67 | USP14 (0.40) | ALOX12USP14NPC1RAB9AMEN1 | |
| SCHEMBL7650895 | 0.67 | KDM4E (0.47) | HDAC3HDAC1NPC1RAB9AALDH1A1 | |
| SCHEMBL1743684 | 0.67 | CYP3A4 (0.49) | USP14NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL6472720 | 0.66 | KDM4E (0.43) | USP14NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2853361 | 0.66 | ALDH1A1 (0.38) | USP14KLKB1ALDH1A1 | |
| SCHEMBL31139989 | 0.66 | NUDT1 (0.30) | — | |
| SCHEMBL2865322 | 0.65 | ALDH1A1 (0.37) | USP14NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29411261 | 0.65 | RECQL (0.47) | HDAC4HDAC1HDAC6USP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993000906-A1 | MUSCARINIC ANTAGONISTS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-01-21 | — | — | WO | disclosed |