SCHEMBL501365

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Trifluoromethanesulfonic Acid SCHEMBL9680879	0.87	THRB (0.36)	THRBTHRAKDM4EMAPTHPGD
	SCHEMBL9543319	0.80	THRB (0.49)	THRBTHRAKDM4EMAPTHPGD
	SCHEMBL3841280	0.78	THRB (0.56)	THRBTHRAKDM4EMAPTHPGD
	SCHEMBL29413361	0.78	THRB (0.56)	THRBTHRAKDM4EMAPTHPGD
	SCHEMBL30249447	0.78	PTGS2 (0.53)	KDM4EMAPTHPGDHSD17B10ESR1
	SCHEMBL246707	0.78	THRB (0.47)	THRBTHRAKDM4EMAPTHPGD
	SCHEMBL3203771	0.78	PTGS2 (0.53)	KDM4EMAPTHPGDHSD17B10ESR1
	SCHEMBL3198775	0.77	KMT2A (0.56)	MAPTHSD17B10ESR1ESR2TDP1
	SCHEMBL7170318	0.75	THRB (0.50)	THRBTHRAKDM4EMAPTHPGD
	SCHEMBL31005112	0.75	PTGS2 (0.53)	KDM4EMAPTHPGDHSD17B10ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.