Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568529 | 0.81 | DHFR (0.35) | DHFRRORC | |
| SCHEMBL9540699 | 0.72 | DHFR (0.34) | DHFRSLC2A1RORC | |
| SCHEMBL8854243 | 0.67 | ABCC9 (0.40) | ABCC9KCNJ11 | |
| SCHEMBL19135849 | 0.65 | DHFR (0.43) | DHFRSLC2A1 | |
| SCHEMBL11236635 | 0.63 | TDP1 (0.44) | ABCC9KCNJ11 | |
| SCHEMBL9568686 | 0.63 | MAOB (0.50) | — | |
| SCHEMBL11691720 | 0.63 | ABCC9 (0.38) | ABCC9KCNJ11RORC | |
| SCHEMBL8898310 | 0.62 | EPHX1 (0.50) | SLC2A1 | |
| SCHEMBL8896455 | 0.62 | SIRT2 (0.43) | ABCC9KCNJ11 | |
| SCHEMBL13523189 | 0.61 | GAA (0.43) | ABCC9KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010119-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |
| EP-0542497-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |