Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8754981 | 0.89 | KDM4E (0.47) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL1325377 | 0.86 | SRD5A1 (0.41) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL1479090 | 0.84 | ALDH1A1 (0.48) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL29645124 | 0.83 | THRB (0.42) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL9419211 | 0.83 | ALDH1A1 (0.45) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL17694444 | 0.83 | THRB (0.42) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL8824319 | 0.83 | GABRA1 (0.44) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL9614734 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL27669490 | 0.81 | MTNR1A (0.40) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL14058648 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1TSHRHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |