Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543647 | 0.74 | GRIK1 (0.33) | GPR119 | |
| SCHEMBL9543675 | 0.72 | ELOVL6 (0.33) | — | |
| SCHEMBL15625371 | 0.70 | EPHX2 (0.41) | HRH3EPHX2NAAAKDM5AGPR119 | |
| SCHEMBL7420310 | 0.69 | SCN4A (0.43) | SCN9A | |
| SCHEMBL12094627 | 0.68 | GPR119 (0.61) | NAAAGPR119 | |
| SCHEMBL29749275 | 0.67 | GPR119 (0.62) | EPHX2KDM5AGPR119 | |
| SCHEMBL1087898 | 0.67 | GPR119 (0.62) | EPHX2KDM5AGPR119 | |
| Acetic Acid SCHEMBL4325103 | 0.67 | HRH1 (0.49) | EPHX2NAAAKDM5AHCRTR1HCRTR2 | |
| SCHEMBL6344507 | 0.67 | EPHX2 (0.44) | EPHX2KDM5AGPR119 | |
| SCHEMBL3001240 | 0.67 | GPR119 (0.52) | EPHX2KDM5AGPR119HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018003-A1 | SUBSTITUED PIPECOLINIC ACID DERIVATIVES AS HIV PROTEASE INHIBITORS | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-16 | — | — | WO | disclosed |