Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543406 | 0.93 | PTPN1 (0.38) | PTPN1HDAC8 | |
| SCHEMBL9544819 | 0.92 | DRD4 (0.38) | DRD2DRD4ALOX5AP | |
| SCHEMBL9542741 | 0.91 | CFTR (0.37) | CFTRHDAC8 | |
| SCHEMBL9542649 | 0.89 | PREP (0.39) | PTPN1HDAC8 | |
| SCHEMBL9543445 | 0.88 | DRD4 (0.41) | DRD2DRD4LMNAALOX5AP | |
| SCHEMBL9543221 | 0.88 | DRD2 (0.35) | DRD2DRD4POLB | |
| SCHEMBL9543510 | 0.87 | ALDH1A1 (0.43) | DRD2DRD4HDAC8 | |
| SCHEMBL9544446 | 0.86 | HDAC8 (0.36) | PTPN1HDAC8 | |
| SCHEMBL9542714 | 0.86 | PREP (0.41) | PTPN1HDAC8 | |
| SCHEMBL9544953 | 0.84 | ACE (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | claimed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |