Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545071 | 0.90 | DRD2 (0.37) | DRD2DRD4HTR1AHTR7OPRM1 | |
| SCHEMBL9543406 | 0.90 | PTPN1 (0.38) | — | |
| SCHEMBL9544819 | 0.90 | DRD4 (0.38) | DRD2DRD4TDP1L3MBTL1 | |
| SCHEMBL9542649 | 0.88 | PREP (0.39) | — | |
| SCHEMBL9543619 | 0.88 | DRD2 (0.38) | DRD2DRD4POLB | |
| SCHEMBL9545266 | 0.87 | DRD2 (0.39) | DRD2DRD4CYP2C19OPRM1OPRL1 | |
| SCHEMBL9543247 | 0.86 | POLB (0.39) | POLBHTR1AHTR7 | |
| SCHEMBL9543510 | 0.86 | ALDH1A1 (0.43) | DRD2DRD4 | |
| SCHEMBL9544446 | 0.85 | HDAC8 (0.36) | OPRM1OPRL1 | |
| SCHEMBL9542741 | 0.85 | CFTR (0.37) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | claimed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |