Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5564662 | 0.87 | TSHR (0.44) | PYGLTSHRPTPN1KMT2ACYP11B1 | |
| SCHEMBL9558295 | 0.85 | KMT2A (0.51) | PYGLTSHRKMT2ASIRT2CDK8 | |
| SCHEMBL5522734 | 0.84 | ALDH1A1 (0.50) | TSHRKMT2AMAPTL3MBTL1CYP4F2 | |
| SCHEMBL3066819 | 0.84 | TSHR (0.58) | PYGLTSHRPTPN1CYP11B1CYP11B2 | |
| SCHEMBL1745477 | 0.81 | CA2 (0.52) | ALOX5OR51E2 | |
| SCHEMBL14461366 | 0.81 | RAB9A (0.48) | PYGLTSHRPTPN1CYP11B1CYP11B2 | |
| SCHEMBL23665899 | 0.80 | CYP3A4 (0.49) | PYGLTSHRPTPN1KMT2ACYP11B1 | |
| SCHEMBL26641492 | 0.80 | CDK8 (0.52) | KMT2AMAPTCDK8CLK4ALOX5 | |
| SCHEMBL30643734 | 0.80 | CDK8 (0.52) | KMT2AMAPTCDK8CLK4ALOX5 | |
| SCHEMBL24133079 | 0.80 | L3MBTL1 (0.41) | PYGLTSHRKMT2ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260277-A | Cell receptor antagonists | TANABE SEIYAKU CO., LTD. (JP) | 1993-11-09 | — | — | US | disclosed |
| WO-1993008823-A1 | GUANIDINYL AND RELATED CELL ADHESION MODULATION COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 1993-05-13 | — | — | WO | disclosed |