Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495928 | 0.75 | KDM4E (0.40) | MAPTTSHRGAAKDM4ESMN1; SMN2 | |
| SCHEMBL1425480 | 0.72 | KDM4E (0.38) | MAPTGAAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL1425313 | 0.72 | MAPT (0.38) | MAPTTSHRGAAKDM4ESMN1; SMN2 | |
| SCHEMBL22438832 | 0.70 | ADORA1 (0.47) | MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9933231 | 0.69 | NOS2 (0.41) | MAPTGAAKDM4ESMN1; SMN2LMNA | |
| SCHEMBL8380828 | 0.66 | ALDH1A1 (0.50) | MAPTTSHRGAAKDM4ESMN1; SMN2 | |
| SCHEMBL10656780 | 0.66 | HSP90AA1 (0.50) | MAPTTSHRGAAKDM4ESMN1; SMN2 | |
| SCHEMBL10656068 | 0.66 | HSP90AA1 (0.52) | MAPTTSHRGAAKDM4ESMN1; SMN2 | |
| SCHEMBL1329577 | 0.66 | NOS1 (0.46) | MAPTTSHRGAAKDM4ESMN1; SMN2 | |
| SCHEMBL11934337 | 0.66 | HSP90AA1 (0.43) | MAPTKDM4ESMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018035-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |