Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544370 | 1.00 | POLB (0.53) | POLBMAPK1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL8863233 | 0.96 | POLB (0.56) | POLBMAPK1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL23485199 | 0.88 | POLB (0.61) | POLBALDH1A1FKBP1A | |
| SCHEMBL2678864 | 0.88 | POLB (0.61) | POLBALDH1A1FKBP1A | |
| SCHEMBL7433978 | 0.88 | POLB (0.61) | POLBALDH1A1FKBP1A | |
| SCHEMBL30564487 | 0.88 | POLB (0.61) | POLBALDH1A1FKBP1A | |
| SCHEMBL6017192 | 0.87 | TSHR (0.52) | POLBMAPK1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL7310404 | 0.86 | POLB (0.62) | POLBL3MBTL1ALDH1A1TSHRFKBP1A | |
| SCHEMBL8482480 | 0.86 | POLB (0.62) | POLBL3MBTL1ALDH1A1TSHRFKBP1A | |
| SCHEMBL8477557 | 0.86 | POLB (0.62) | POLBL3MBTL1ALDH1A1TSHRFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993017681-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |