Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547215 | 0.92 | POLB (0.49) | POLBKCNH2NR4A2SSTR5TACR2 | |
| SCHEMBL10549253 | 0.87 | CCR3 (0.52) | POLBKCNH2NR4A2SSTR5TACR2 | |
| SCHEMBL9740976 | 0.84 | SSTR5 (0.65) | KCNH2NR4A2SSTR5TP53MAPT | |
| SCHEMBL10546904 | 0.83 | HRH1 (0.46) | POLBKCNH2NR4A2SSTR5TP53 | |
| Oxalic Acid SCHEMBL9537142 | 0.82 | HPGD (0.43) | POLBTP53MAPTGAASMN1; SMN2 | |
| Oxalic Acid SCHEMBL9537131 | 0.82 | HPGD (0.43) | POLBTP53MAPTGAASMN1; SMN2 | |
| SCHEMBL10552594 | 0.81 | LMNA (0.54) | POLBTP53MAPTLMNA | |
| SCHEMBL9537486 | 0.81 | POLB (0.48) | POLBKCNH2NR4A2SSTR5TP53 | |
| SCHEMBL9536186 | 0.80 | MAPT (0.56) | POLBSSTR5TP53MAPTGAA | |
| SCHEMBL9536847 | 0.80 | KCNH2 (0.49) | POLBKCNH2NR4A2SSTR5TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014083-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-22 | — | — | WO | disclosed |