Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542195 | 0.91 | MEN1 (0.40) | KMT2AMEN1ALDH1A1GLAALOX15 | |
| SCHEMBL9584911 | 0.89 | MEN1 (0.39) | KMT2AMEN1ALDH1A1GLAALOX15 | |
| SCHEMBL9542307 | 0.86 | MEN1 (0.42) | KMT2AMEN1ALDH1A1GLAALOX15 | |
| SCHEMBL9541782 | 0.82 | KMT2A (0.41) | KMT2AMEN1ALDH1A1GLACYP1A2 | |
| SCHEMBL9543443 | 0.80 | TSHR (0.43) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9541760 | 0.78 | TUBB4A (0.51) | KMT2AMEN1TDP1POLBMAPT | |
| SCHEMBL9542205 | 0.77 | TSHR (0.43) | KMT2AMEN1CYP1A2CYP3A4GAA | |
| SCHEMBL9544531 | 0.77 | KMT2A (0.37) | KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9542171 | 0.77 | GAA (0.46) | KMT2AMEN1CYP1A2CYP3A4GAA | |
| SCHEMBL9543513 | 0.77 | HIF1A (0.43) | ALOX15TSHRMAPTSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |