Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542307 | 0.90 | MEN1 (0.42) | TSHRMCHR1MAPTALOX15SLC6A9 | |
| SCHEMBL9540800 | 0.87 | ALOX15 (0.47) | HIF1ATSHRMAPTALOX15HSD17B10 | |
| SCHEMBL9540786 | 0.86 | ALOX15 (0.45) | HIF1ATSHRTXNRD1MAPTALOX15 | |
| SCHEMBL9542198 | 0.83 | GAA (0.47) | HIF1ATSHRMCHR1MAPTNPC1 | |
| SCHEMBL9544546 | 0.79 | TRPM8 (0.55) | TSHRNPC1RAB9A | |
| SCHEMBL10453097 | 0.79 | SLC6A9 (0.51) | MAPTALOX15NPC1RAB9ASLC6A9 | |
| SCHEMBL9542195 | 0.79 | MEN1 (0.40) | TSHRTXNRD1ALOX15SLC6A9 | |
| SCHEMBL9541760 | 0.77 | TUBB4A (0.51) | MAPTSLC6A9 | |
| SCHEMBL9584911 | 0.77 | MEN1 (0.39) | TSHRTXNRD1MAPTALOX15SLC6A9 | |
| SCHEMBL9543443 | 0.77 | TSHR (0.43) | TSHRTXNRD1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | claimed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | claimed |
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |