Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540773 | 0.87 | SLC6A2 (0.42) | TSHRKMT2AMEN1ALDH1A1SLC6A2 | |
| SCHEMBL9199484 | 0.86 | TSHR (0.44) | TSHRKMT2AMEN1MAPK1SLC6A2 | |
| SCHEMBL9542239 | 0.84 | TSHR (0.42) | TSHRALDH1A1SLC6A2SLC6A4SLC6A9 | |
| SCHEMBL9540766 | 0.84 | SLC6A2 (0.44) | TSHRKMT2AMEN1ALDH1A1SLC6A2 | |
| SCHEMBL9540877 | 0.82 | SLC6A9 (0.47) | TSHRKMT2AMEN1SLC6A2SLC6A4 | |
| SCHEMBL9541782 | 0.82 | KMT2A (0.41) | TSHRKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL9541760 | 0.81 | TUBB4A (0.51) | KMT2AMEN1SLC6A9MAPT | |
| SCHEMBL1354744 | 0.81 | TSHR (0.61) | TSHRKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL9544534 | 0.80 | KMT2A (0.38) | TSHRKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL9542205 | 0.80 | TSHR (0.43) | TSHRKMT2AMEN1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |