Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 7/20 | 0.51 |
| ▸ | TUBB | P07437 | 7/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540822 | 0.86 | THRB (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9542171 | 0.86 | GAA (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9584306 | 0.85 | SLC6A9 (0.44) | MEN1KMT2ATDP1POLBMAPT | |
| SCHEMBL9542307 | 0.85 | MEN1 (0.42) | MEN1KMT2ATDP1POLBMAPT | |
| SCHEMBL9542205 | 0.84 | TSHR (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9542195 | 0.83 | MEN1 (0.40) | MEN1KMT2ATDP1POLBSIRT5 | |
| SCHEMBL9541768 | 0.83 | ALDH1A1 (0.42) | MEN1KMT2ATDP1POLBMAPT | |
| SCHEMBL9543443 | 0.81 | TSHR (0.43) | MEN1KMT2AMAPTSLC6A9 | |
| SCHEMBL10453097 | 0.81 | SLC6A9 (0.51) | MEN1KMT2APOLBMAPTSLC6A9 | |
| SCHEMBL9542239 | 0.80 | TSHR (0.42) | POLBMAPTSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | claimed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | claimed |
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |