Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542258 | 0.88 | NPC1 (0.55) | NPC1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9542171 | 0.84 | GAA (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9543471 | 0.81 | MEN1 (0.42) | MAPTMEN1KMT2AALDH1A1SLC6A2 | |
| SCHEMBL9543496 | 0.81 | MEN1 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9542198 | 0.81 | GAA (0.47) | NPC1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9540799 | 0.80 | TRPM8 (0.51) | NPC1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9540773 | 0.78 | SLC6A2 (0.42) | NPC1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10453097 | 0.76 | SLC6A9 (0.51) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9540692 | 0.76 | POLB (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9542254 | 0.74 | TRPM8 (0.55) | NPC1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |