Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543443 | 0.87 | TSHR (0.43) | SLC6A2SLC6A4NPC1GAACYP1A2 | |
| SCHEMBL9540766 | 0.81 | SLC6A2 (0.44) | SLC6A2SLC6A4NPC1MEN1MAPT | |
| SCHEMBL9540877 | 0.80 | SLC6A9 (0.47) | SLC6A2SLC6A4NPC1GAACYP1A2 | |
| SCHEMBL9543471 | 0.79 | MEN1 (0.42) | SLC6A2SLC6A4APOBEC3GS1PR1S1PR3 | |
| SCHEMBL9544581 | 0.78 | NPC1 (0.44) | SLC6A2SLC6A4NPC1GAAS1PR1 | |
| SCHEMBL9199484 | 0.78 | TSHR (0.44) | SLC6A2SLC6A4GAACYP1A2CYP3A4 | |
| SCHEMBL13434665 | 0.78 | SLC6A2 (0.48) | SLC6A2SLC6A4 | |
| SCHEMBL9542258 | 0.78 | NPC1 (0.55) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL3487180 | 0.77 | SLC6A2 (0.48) | SLC6A2SLC6A4 | |
| SCHEMBL10453097 | 0.77 | SLC6A9 (0.51) | SLC6A2SLC6A4NPC1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |