Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544581 | 0.88 | NPC1 (0.44) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9540799 | 0.86 | TRPM8 (0.51) | NPC1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9543496 | 0.83 | MEN1 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10453097 | 0.83 | SLC6A9 (0.51) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9542198 | 0.80 | GAA (0.47) | NPC1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9540692 | 0.80 | POLB (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9542171 | 0.79 | GAA (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9542254 | 0.78 | TRPM8 (0.55) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9540773 | 0.78 | SLC6A2 (0.42) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12917871 | 0.76 | ALDH1A1 (0.58) | NPC1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |