Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | F2R | P25116 | 3/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842953 | 0.90 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19152067 | 0.86 | CYP3A4 (0.53) | L3MBTL1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8415139 | 0.79 | MEN1 (0.62) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL9814087 | 0.77 | LMNA (0.73) | L3MBTL1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8614195 | 0.77 | L3MBTL1 (0.59) | L3MBTL1LMNAPOLB | |
| SCHEMBL8278749 | 0.77 | F2R (0.65) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL30764851 | 0.77 | L3MBTL1 (0.59) | L3MBTL1LMNAPOLB | |
| SCHEMBL14035376 | 0.76 | ALDH1A1 (0.62) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1531710 | 0.76 | ALOX5 (0.59) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8278746 | 0.75 | TP53 (0.72) | ALDH1A1HPGDMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020807-A1 | AMINES AS INHIBITORS OF SQUALENE SYNTHASE | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |