Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397940 | 0.80 | ALDH1A1 (1.00) | LMNAMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL9787602 | 0.79 | ALDH1A1 (0.60) | LMNAMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL1792654 | 0.69 | KMT2A (0.64) | LMNAMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL30914450 | 0.69 | KMT2A (0.48) | LMNAALDH1A1KMT2AHTTTSHR | |
| SCHEMBL19710110 | 0.69 | L3MBTL1 (0.77) | LMNAALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL3190404 | 0.69 | KMT2A (0.48) | LMNAALDH1A1KMT2AHTTTSHR | |
| SCHEMBL10031606 | 0.67 | POLB (0.66) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3456302 | 0.65 | AKR1C3 (0.77) | LMNAMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL31086922 | 0.65 | ALDH1A1 (0.72) | LMNAALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL9854038 | 0.65 | PTAFR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5051381-A | — | — | None | — | — | JP | disclosed |
| JP-H0551381-A | THIAZOLIDINE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1993-03-02 | — | — | JP | disclosed |