Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.55 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.55 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.55 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545043 | 0.90 | KMT2A (0.54) | FFAR1FFAR4PLAAT3PLAAT5PLAAT2 | |
| Methyl 3-Phenylpropanoate SCHEMBL213543 | 0.85 | KEAP1 (0.70) | FFAR1FFAR4ALDH1A1SMN1; SMN2KEAP1 | |
| Methyl 3-Phenylpropanoate SCHEMBL27506579 | 0.84 | KEAP1 (0.68) | FFAR1FFAR4ALDH1A1SMN1; SMN2KEAP1 | |
| Methyl 3-Phenylpropanoate SCHEMBL6734679 | 0.84 | KEAP1 (0.68) | FFAR1FFAR4ALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL80581 | 0.84 | ALDH1A1 (0.67) | FFAR1FFAR4PLAAT3PLAAT5PLAAT2 | |
| Phenyl Propionic Acid SCHEMBL28549085 | 0.84 | FFAR1 (0.59) | FFAR1FFAR4ALDH1A1KMT2ATHRA | |
| Phenyl Propionic Acid SCHEMBL28910944 | 0.84 | RAB9A (0.59) | FFAR1FFAR4ALDH1A1KEAP1TDP1 | |
| Phenyl Propionic Acid SCHEMBL28544542 | 0.84 | FFAR1 (0.59) | FFAR1FFAR4KEAP1POLBSIRT2 | |
| Phenyl Propionic Acid SCHEMBL28551157 | 0.83 | FFAR4 (0.57) | FFAR1FFAR4ALDH1A1KMT2ATHRA | |
| Phenyl Propionic Acid SCHEMBL28549079 | 0.82 | RAB9A (0.60) | FFAR1FFAR4ALDH1A1KEAP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438238-B | Synthetic method of dihydrocinnamate compound | 陕西师范大学 | 2021-04-13 | — | — | CN | disclosed |