Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9544813 | 0.81 | PNP (0.34) | PNPMEN1KMT2A | |
| SCHEMBL9544019 | 0.73 | PNP (0.36) | XDHKDM4EALDH1A1LMNAGLA | |
| Hydrochloric Acid SCHEMBL9545316 | 0.71 | XDH (0.33) | XDHKDM4EHSD17B10PNPNPC1 | |
| SCHEMBL9545341 | 0.66 | PNP (0.35) | PNPMEN1KMT2ATYMSQTRT1 | |
| SCHEMBL2982031 | 0.66 | HPRT1 (0.53) | KDM4EALDH1A1GLAPMP22HSD17B10 | |
| SCHEMBL9544092 | 0.65 | TYMS (0.34) | MEN1KMT2ATYMSQTRT1 | |
| SCHEMBL9544423 | 0.65 | HSD17B10 (0.33) | XDHKDM4EHSD17B10PNPNPC1 | |
| SCHEMBL9545267 | 0.64 | XDH (0.35) | XDHKDM4EPNPTYMSNPC1 | |
| SCHEMBL8798202 | 0.62 | HPRT1 (0.49) | KDM4EALDH1A1GLAPMP22HSD17B10 | |
| SCHEMBL1765839 | 0.62 | HPRT1 (0.41) | KDM4EALDH1A1GLAPMP22HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020075-A1 | 8-SUBSTITUTED-N5-DEAZAPTERINS AS ANTIFOLATES | THE UNIVERSITY OF SYDNEY (AU) | 1993-10-14 | — | — | WO | disclosed |