Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544945 | 0.93 | ACE (0.39) | ALDH1A1 | |
| SCHEMBL9544292 | 0.92 | ALDH1A1 (0.48) | ALDH1A1DRD2DRD4SMPD1MAPT | |
| SCHEMBL9542586 | 0.91 | LMNA (0.41) | ALDH1A1LMNAMAPT | |
| SCHEMBL9544364 | 0.91 | DRD4 (0.45) | ALDH1A1DRD2DRD4 | |
| SCHEMBL9543652 | 0.88 | ACE (0.38) | ALDH1A1 | |
| SCHEMBL9542696 | 0.86 | LMNA (0.42) | DRD2DRD4LMNAMAPT | |
| SCHEMBL9542919 | 0.85 | DRD2 (0.40) | DRD2DRD4LMNASMN1; SMN2 | |
| SCHEMBL9544136 | 0.85 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL9544913 | 0.84 | ACE (0.41) | — | |
| SCHEMBL9543297 | 0.84 | DRD2 (0.38) | ALDH1A1DRD2DRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |