Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543445 | 0.92 | DRD4 (0.41) | DRD2DRD4LMNATP53SMN1; SMN2 | |
| SCHEMBL9542586 | 0.91 | LMNA (0.41) | LMNA | |
| SCHEMBL9544364 | 0.91 | DRD4 (0.45) | DRD2DRD4 | |
| SCHEMBL9544945 | 0.90 | ACE (0.39) | — | |
| SCHEMBL9543652 | 0.86 | ACE (0.38) | — | |
| SCHEMBL9543297 | 0.85 | DRD2 (0.38) | DRD2DRD4LMNA | |
| SCHEMBL9545334 | 0.85 | ALDH1A1 (0.48) | DRD2DRD4LMNASMN1; SMN2 | |
| SCHEMBL9543619 | 0.83 | DRD2 (0.38) | DRD2DRD4LMNA | |
| SCHEMBL9542891 | 0.83 | CTSL (0.39) | TP53 | |
| SCHEMBL9543607 | 0.83 | ALDH1A1 (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |