Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545767 | 0.90 | LMNA (0.44) | TSHRALDH1A1HSD17B10CLCN2TDP1 | |
| SCHEMBL7444828 | 0.87 | ALDH1A1 (0.51) | TSHRNLRP3ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL29028154 | 0.85 | TSHR (0.44) | TSHRGABRA1GABRB2NLRP3ALDH1A1 | |
| Benzene SCHEMBL28861656 | 0.85 | ALDH1A1 (0.50) | TSHRALDH1A1HSD17B10CLCN2HTT | |
| SCHEMBL28351017 | 0.84 | CASP3 (0.53) | ALDH1A1CYP1A2TDP1L3MBTL1HTT | |
| SCHEMBL1539077 | 0.82 | TSHR (0.42) | TSHRGABRA1GABRB2NLRP3ALDH1A1 | |
| SCHEMBL28032864 | 0.82 | TSHR (0.39) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL28708772 | 0.82 | GABRA1 (0.48) | TSHRGABRA1GABRB2NLRP3ALDH1A1 | |
| SCHEMBL739158 | 0.82 | TSHR (0.52) | TSHRGABRA1GABRB2ALDH1A1HSD17B10 | |
| SCHEMBL28037410 | 0.81 | TSHR (0.38) | TSHRALDH1A1HSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5186646-A | — | — | None | — | — | JP | disclosed |
| JP-H05186646-A | POLYPROPYLENE-BASED RESIN COMPOSITION | TOSOH CORP | 1993-07-27 | — | — | JP | disclosed |
| EP-0507576-A1 | Polypropylene-based resin compositions | TOSOH CORPORATION (JP) | 1992-10-07 | — | — | EP | disclosed |