Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498147 | 0.89 | ALDH1A1 (0.74) | ALDH1A1ALOX15KDM4EHPGDMAPT | |
| SCHEMBL7440681 | 0.87 | ALDH1A1 (0.62) | ALDH1A1ALOX15KDM4ETSHRHPGD | |
| SCHEMBL875217 | 0.83 | KDM4E (0.65) | ALDH1A1ALOX15KDM4ETSHRHPGD | |
| SCHEMBL5707058 | 0.83 | ALDH1A1 (0.43) | ALDH1A1ALOX15KDM4ETSHRHPGD | |
| SCHEMBL5782883 | 0.81 | NPC1 (0.47) | ALDH1A1ALOX15KDM4EHPGDMAPT | |
| SCHEMBL10894049 | 0.81 | ALDH1A1 (0.42) | ALDH1A1ALOX15KDM4ETSHRHPGD | |
| SCHEMBL11101821 | 0.81 | MEN1 (0.50) | ALDH1A1ALOX15KDM4ETSHRHPGD | |
| SCHEMBL734717 | 0.81 | HPGD (0.50) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL1498123 | 0.81 | CES2 (0.65) | ALDH1A1KDM4ETSHRHPGDCES2 | |
| SCHEMBL826784 | 0.81 | MAPT (0.62) | ALDH1A1ALOX15KDM4ETSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025212-A1 | POLYOXYMETHYLENE-OXYETHYLENE COPOLYMERS IN CONJUNCTION WITH BIOMOLECULES | AMGEN INC. (US) | 1993-12-23 | — | — | WO | disclosed |