Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.61 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545865 | 0.83 | ALDH1A1 (0.53) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL3743759 | 0.80 | ALDH1A1 (0.50) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| Salicylamide SCHEMBL21646 | 0.79 | KDM4E (1.00) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| Salicylamide SCHEMBL27497234 | 0.79 | KDM4E (1.00) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| Salicylamide SCHEMBL29384763 | 0.79 | KDM4E (1.00) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| 2,2'-Dihydroxybenzphenone SCHEMBL29572496 | 0.78 | HPGD (0.67) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| 2,2'-Dihydroxybenzphenone SCHEMBL18422 | 0.78 | HPGD (0.67) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL29861559 | 0.78 | KDM4E (0.67) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL9797513 | 0.78 | KDM4E (0.67) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| Salicylamide SCHEMBL18729462 | 0.77 | KDM4E (0.95) | KDM4EHPGDALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198426-B2 | Use of 5 pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | claimed |
| EP-2658538-A2 | PREPARATIONS FOR TOPICAL PREVENTION AND/OR TREATMENT OF ORAL ALLERGIC SYMPTOMS DUE TO ORAL CONTACT WITH FRUITS AND/OR VEGETABLES | Harish, M.D. Ziv (US) | 2013-11-06 | — | — | EP | claimed |
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | claimed |
| WO-2012092594-A2 | PREPARATIONS FOR TOPICAL PREVENTION AND/OR TREATMENT OF ORAL ALLERGIC SYMPTOMS DUE TO ORAL CONTACT WITH FRUITS AND/OR VEGETABLES | HARISH ZIV M D (US) | 2012-07-05 | — | — | WO | claimed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | claimed |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2011-03-17 | — | — | US | claimed |
| US-20100168185-A1 | Use of 5-pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | BAYER CORPSCIENCE AG (DE) | 2010-07-01 | — | — | US | claimed |
| EP-2198710-A1 | Use of 5-pyridin-4yl-(1,3) thiazoles for combating phytopathogenic fungi | Bayer CropScience AG (DE) | 2010-06-23 | — | — | EP | claimed |
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| JP-63161052-A | — | — | None | — | — | JP | disclosed |
| US-11801252-B2 | Pharmaceutical composition | JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) | 2023-10-31 | — | — | US | disclosed |
| WO-2023161939-A1 | FORMULATIONS COMPRISING ACID-NEUTRALIZING POLYMER FOR ORAL ADMINISTRATION OF GLUCAGON-LIKE PEPTIDE-1 AND ANALOGS THEREOF | ENTERA BIO LTD. (IL) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023161935-A1 | FORMULATIONS COMPRISING ACID-NEUTRALIZING POLYMER FOR ORAL ADMINISTRATION OF GROWTH HORMONE | ENTERA BIO LTD. (IL) | 2023-08-31 | — | — | WO | disclosed |
| EP-0037563-A1 | Sulfur dyes of the carbazole series, their preparation and application, as well as intermediate compounds | CASSELLA Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-3996282-A | Water-soluble quaternary ammonium dyestuffs | STERLING DRUG INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3994987-A | Metal deactivators as adhesion promotors for vulcanizable elastomers to metals | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3935182-A | Water-soluble quaternary ammonium heterocyclic azo dyestuffs | STERLING DRUG INC. (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168185-A1 | Use of 5-pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | PIR, PNPO, PDXK | KDM4E 941/4885HPGD 2948/4885ALDH1A1 2137/4885 |
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | KDM4E 1582/4885HPGD 1253/4885ALDH1A1 123/4885 |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | PDE4A, PDE4B, PDE4D | KDM4E 1159/4885HPGD 1811/4885ALDH1A1 1228/4885 |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | KDM4E 1240/4885HPGD 1657/4885ALDH1A1 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.