SCHEMBL9545924

SCHEMBL9545924

CCc1[c]ccc(-c2ccccc2C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.41
MCL1 Q07820 1/20 0.41
TRPA1 O75762 1/20 0.36
CTSD P07339 1/20 0.36
BACE1 P56817 1/20 0.36
GRIA1 P42261 1/20 0.35
CACNG8 Q8WXS5 1/20 0.35
HTR1A P08908 1/20 0.35
LCK P06239 1/20 0.35
KDR P35968 1/20 0.35
JAK3 P52333 1/20 0.35
MAPK14 Q16539 1/20 0.35
AR P10275 1/20 0.35
PDK2 Q15119 1/20 0.35
NMT2 O60551 1/20 0.35
NMT1 P30419 1/20 0.35
CA12 O43570 2/20 0.34
CA9 Q16790 2/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8104516 0.83 TRPA1 (0.43) TRPA1
SCHEMBL15636516 0.81 CYP2A6 (0.42) TRPA1BACE1JAK3ARPDK2
SCHEMBL29144747 0.79 TRPA1 (0.40) TRPA1CA12CA9CA1CA2
SCHEMBL8913076 0.79 HTR7 (0.46) HTR7ARPDK2EDNRBEDNRA
SCHEMBL15638352 0.79 MCL1 (0.42) HTR7MCL1TRPA1CTSDBACE1
SCHEMBL1370479 0.78 ALDH1A1 (0.36) MCL1
SCHEMBL374592 0.78 MCL1 (0.45) HTR7MCL1TRPA1CTSDBACE1
SCHEMBL10595614 0.75 MCL1 (0.42) HTR7MCL1TRPA1CTSDBACE1
SCHEMBL8125021 0.75 MCL1 (0.42) HTR7MCL1TRPA1CTSDBACE1
SCHEMBL456425 0.74 CA12 (0.39) HTR7MCL1TRPA1CTSDBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993024468-A1 PYRIMIDINYL- AND TRIAZINYL- SALICYL- AND PICOLYLAMIDES AND THE USE, AS HERBICIDES, AND PREPARATION THEREOF CIBA-GEIGY AG (CH) 1993-12-09 WO disclosed