Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280106 | 0.86 | MAOB (0.58) | MAOBLMNAL3MBTL1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9547438 | 0.85 | LMNA (0.53) | ADRA1ALMNAL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL26633553 | 0.84 | MAOB (0.56) | MAOBLMNAL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL9547470 | 0.82 | F2 (0.65) | ADRA1A | |
| SCHEMBL7213360 | 0.79 | TP53 (0.59) | ADRA1ALMNANPC1RAB9AMAPT | |
| SCHEMBL20333167 | 0.79 | PRMT1 (0.53) | ADRA1A | |
| SCHEMBL9547440 | 0.78 | ALDH1A1 (0.55) | ADRA1ALMNAPOLBNPC1RAB9A | |
| SCHEMBL8994969 | 0.77 | PRMT1 (0.51) | ADRA1A | |
| SCHEMBL3743320 | 0.77 | GAA (0.51) | RAB9ALTA4H | |
| SCHEMBL8994951 | 0.77 | DRD2 (0.56) | LMNAL3MBTL1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246965-A | Leukotriene antagonist | CIBA-GEIGY (US) | 1993-09-21 | — | — | US | disclosed |
| EP-0518818-A2 | Arylethers, their manufacture and use as medicament | CIBA-GEIGY AG (CH) | 1992-12-16 | — | — | EP | disclosed |