SCHEMBL5317014

SCHEMBL5317014

Nc1ccc(C(=O)CCl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 3/20 0.64
ALDH1A1 P00352 5/20 0.60
HIF1A Q16665 3/20 0.60
TRPA1 O75762 1/20 0.60
MAPK1 P28482 1/20 0.60
TP53 P04637 1/20 0.52
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 5/20 0.48
POLB P06746 3/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
LMNA P02545 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
MAOA P21397 1/20 0.45
CYP19A1 P11511 1/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11480265 0.87 GSK3B (0.80) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL5317013 0.81 GSK3B (0.64) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL10886301 0.80 GSK3B (0.70) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL11365527 0.80 MAPT (0.56) ALDH1A1HIF1AMAPK1MEN1KMT2A
SCHEMBL3373429 0.78 LMNA (0.47) ALDH1A1HIF1AMEN1KMT2AMAPT
SCHEMBL2968369 0.78 GSK3B (0.67) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL5787064 0.78 GSK3B (0.67) GSK3BALDH1A1HIF1ATRPA1MAPK1
SCHEMBL9547546 0.78 LMNA (0.47) GSK3BHIF1AMEN1KMT2AMAPT
SCHEMBL3181886 0.78 LMNA (0.47) HIF1AMEN1KMT2AMAPTPOLB
SCHEMBL953871 0.78 GSK3B (1.00) GSK3BALDH1A1HIF1ATRPA1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102426-A Wide-absorption polymerizable ketene photoinitiator and preparation method and application thereof 合肥工业大学 2023-05-12 CN claimed
CN-109096126-A A kind of deuterium-labeled D9The synthetic method of clenobuterol hydrochloride 东莞暨南大学研究院 2018-12-28 CN claimed
CN-108929276-A A method of pyrimidines are prepared by methyl ketone compounds and nitrile compounds 湖南大学 2018-12-04 CN claimed
WO-2015157360-A1 PROCESSES TO MAKE PROTEIN KINASE INHIBITORS ABBVIE INC. (US) 2015-10-15 WO claimed
EP-0430434-B1 Process for the preparation of fluoroaromatic and fluoroheteroaromatic compounds ZENECA LTD (GB) 1994-09-14 EP claimed
EP-0430434-A2 Process for the preparation of fluoroaromatic and fluoroheteroaromatic compounds ZENECA LIMITED (GB) 1991-06-05 EP claimed
US-20260070898-A1 PROCESS FOR THE PREPARATION OF FURAZANOBENZIMIDAZOLES AND CRYSTALLINE FORMS THEREOF GLIOBLASTOMA FOUND INC (US) 2026-03-12 US disclosed
CN-116102426-B Wide-absorption polymerizable ketene photoinitiator and preparation method and application thereof 合肥工业大学 2025-04-29 CN disclosed
US-20240352007-A1 PROCESSES FOR THE PREPARATION OF FURAZANOBENZIMIDAZOLES AND CRYSTALLINE FORMS THEREOF BASILEA PHARMACEUTICA INTERNATIONAL LTD, ALLSCHWIL (CH) 2024-10-24 US disclosed
EP-3615529-B1 PROCESSES FOR THE PREPARATION OF FURAZANOBENZIMIDAZOLES AND CRYSTALLINE FORMS THEREOF BASILEA PHARMACEUTICA INT AG ALLSCHWIL (CH) 2024-06-05 EP disclosed
US-11891382-B2 Processes for the preparation of furazanobenzimidazoles and crystalline forms thereof Basilea Pharmaceutica International AG 2024-02-06 US disclosed
CN-116947836-A Method for preparing furazanobenzimidazole and crystal forms thereof 巴斯利尔药物国际股份公司 2023-10-27 CN disclosed
CN-110536890-B Method for preparing furazanobenzimidazole and crystal forms thereof 巴斯利尔药物国际股份公司 2023-08-15 CN disclosed
EP-0052442-B1 HETEROCYCLIC COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-09-11 EP disclosed
US-4503054-A VASODILATORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-03-05 US disclosed
US-4423045-A CARDIOVASCULAR DISORDERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-27 US disclosed
US-4407797-A ANTIULCER AGENT RHONE-POULENC SANTE (FR) 1983-10-04 US disclosed
EP-0052442-A1 Heterocyclic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-05-26 EP disclosed
US-4213898-A FOR POLYACRYLONITRILE SANDOZ LTD. (CH) 1980-07-22 US disclosed
US-4066637-A BASIC DIAMINOPYRIDINE-(3)-AZO DYESTUFFS CIBA-GEIGY CORPORATION (US) 1978-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891382-B2 Processes for the preparation of furazanobenzimidazoles and crystalline forms thereof FANCI, CYP2F1, CYP4F3 GSK3B 2920/4885ALDH1A1 268/4885HIF1A 2718/4885
US-20240352007-A1 PROCESSES FOR THE PREPARATION OF FURAZANOBENZIMIDAZOLES AND CRYSTALLINE FORMS THEREOF FANCI, FANCD2, CYP2F1 GSK3B 2890/4885ALDH1A1 357/4885HIF1A 2691/4885
US-20260070898-A1 PROCESS FOR THE PREPARATION OF FURAZANOBENZIMIDAZOLES AND CRYSTALLINE FORMS THEREOF BRCA1, PRKDC, KIT GSK3B 946/4885ALDH1A1 848/4885HIF1A 1717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.