SCHEMBL30320165

SCHEMBL30320165

Cc1ccc(NC(=O)C(=O)N(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.55
NPC1 O15118 6/20 0.55
KDM4E B2RXH2 2/20 0.55
TDP1 Q9NUW8 1/20 0.52
SMN1; SMN2 Q16637 5/20 0.51
ALDH1A1 P00352 3/20 0.51
POLB P06746 2/20 0.50
HTT P42858 3/20 0.47
KMT2A Q03164 2/20 0.47
KIF11 P52732 1/20 0.46
TGM2 P21980 1/20 0.46
MAPT P10636 4/20 0.45
PPARG P37231 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
NR2E3 Q9Y5X4 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
MEN1 O00255 1/20 0.44
NMT1 P30419 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547555 0.81 TDP1 (0.55) RAB9ANPC1KDM4ETDP1SMN1; SMN2
SCHEMBL6850999 0.80 KDM4E (0.79) RAB9ANPC1KDM4ETDP1SMN1; SMN2
SCHEMBL21551502 0.74 ALDH1A1 (0.44) RAB9ASMN1; SMN2ALDH1A1POLBHTT
SCHEMBL25668512 0.74 TDP1 (0.68) RAB9ANPC1KDM4ETDP1SMN1; SMN2
SCHEMBL6857849 0.74 KDM4E (0.70) RAB9ANPC1KDM4ETDP1SMN1; SMN2
SCHEMBL9613267 0.74 NPC1 (0.64) RAB9ANPC1KDM4ETDP1SMN1; SMN2
SCHEMBL19216503 0.73 TDP1 (0.55) RAB9ANPC1KDM4ETDP1SMN1; SMN2
SCHEMBL9116925 0.73 RAB9A (0.46) RAB9ANPC1KDM4ETDP1SMN1; SMN2
SCHEMBL13763233 0.72 KDM4E (0.68) RAB9ANPC1KDM4ETDP1SMN1; SMN2
SCHEMBL6857293 0.72 ALDH1A1 (0.41) RAB9ATDP1SMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974718-A Panax notoginseng oxamide I and application thereof preparation method and application 江西省蔓三七健康科技有限公司 2023-04-18 CN disclosed