Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.51 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.51 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547764 | 0.95 | LMNA (0.55) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL17602191 | 0.88 | ALOX5 (0.51) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL17602195 | 0.85 | ALOX5 (0.49) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL9121973 | 0.83 | ACACB (0.60) | ACACBFFAR1ENPP3ENPP1GSTP1 | |
| SCHEMBL9547745 | 0.82 | ACACB (0.51) | ACACBFFAR1ENPP3ENPP1GSTP1 | |
| SCHEMBL17602193 | 0.82 | MAPT (0.65) | BCHEGAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9125577 | 0.81 | ACACB (0.62) | ACACBFFAR1ALOX5LMNAMAOB | |
| Biphenyl SCHEMBL9839827 | 0.81 | ACACB (0.59) | ACACBFFAR1ENPP3ENPP1GSTP1 | |
| SCHEMBL197017 | 0.81 | LMNA (0.72) | FFAR1ENPP3ENPP1GSTP1ALOX5 | |
| SCHEMBL10022964 | 0.81 | GSTP1 (0.58) | ACACBFFAR1ENPP3ENPP1GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288297-B1 | OPTICALLY ACTIVE BENZENE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |