Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.64 |
| ▸ | SHBG | P04278 | 4/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833918 | 0.88 | CYP19A1 (0.67) | CYP19A1SHBGSMN1; SMN2LMNAPOLB | |
| SCHEMBL10945246 | 0.82 | CYP19A1 (0.60) | CYP19A1SHBGSMN1; SMN2LMNAPOLB | |
| SCHEMBL20851698 | 0.82 | PGR (0.57) | CYP19A1SHBGESR1PGRAR | |
| SCHEMBL9194138 | 0.82 | PGR (0.57) | CYP19A1SHBGESR1PGRAR | |
| SCHEMBL10902815 | 0.82 | CYP19A1 (0.60) | CYP19A1SHBGESR1PGRAR | |
| SCHEMBL10596342 | 0.82 | CYP19A1 (0.60) | CYP19A1SHBGSMN1; SMN2LMNAPOLB | |
| SCHEMBL10596334 | 0.82 | CYP19A1 (0.60) | CYP19A1SHBGSMN1; SMN2LMNAPOLB | |
| SCHEMBL14946855 | 0.82 | PGR (0.57) | CYP19A1SHBGESR1PGRAR | |
| SCHEMBL9547849 | 0.82 | ESR1 (0.50) | CYP19A1SHBGESR1PGRAR | |
| SCHEMBL9547768 | 0.79 | SHBG (0.47) | CYP19A1SHBGESR1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236913-A | Powerful gestagenic properties and only slight androgenic side effects | AKZO N.V. (NL) | 1993-08-17 | — | — | US | disclosed |
| EP-0210678-B1 | NOVEL LL-METHYLENE-OESTR-15-ENES, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS | AKZO N.V. (NL) | 1989-09-20 | — | — | EP | disclosed |
| EP-0210678-A1 | Novel ll-methylene-oestr-15-enes, processes for their preparation, and pharmaceutical compositions | AKZO N.V. (NL) | 1987-02-04 | — | — | EP | disclosed |